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| 1: The Marijuana Episode |
| Dec 29, 2017 |
| Bill visits a cannabis dispensary in Hollywood and takes a trip through hemp history. Kevin Smith and other panelists weigh weed's pros and cons. |
| 2: Your Computer Is Under Attack |
| Dec 29, 2017 |
| From phishing to malware, Bill uncovers the scams that steal our data. Steve-O talks about the time he exposed himself … to hackers. |
| 3: We Suck at Sleeping |
| Dec 29, 2017 |
| In search of better sleep, correspondents seek out NASA scientists and a professional cuddler. Bill busts myths about naps, dreams and turkey. |
| 4: Sex, Drugs and Superbugs |
| Dec 29, 2017 |
| Bill spreads bad news about antibiotic-resistant gonorrhea and other superbugs. Comedian Ali Wong stops by the studio for a glow-in-the-dark demo. |
| 5: Extinction: Why All Our Friends Are Dying |
| Dec 29, 2017 |
| OK Go and Drew Carey help Bill explain extinction, and the panel reveals how scientists could one day bring extinct species back to life. |
| 6: How to Travel Through Time |
| Dec 29, 2017 |
| Bill breaks down the science of time travel with guests Zach Braff, retired astronaut Scott Kelly and the minds behind "Star Trek" and "Lost." |