Set in 1348 when the Black Death, the deadliest pandemic in human history that killed as many as 200 million people, strikes hard in Florence, a handful of nobles are invited to retreat with their servants to a grand villa in the Italian countryside and await the pestilence with a lavish holiday. But as social rules wear thin, what starts as a wine-soaked sex romp in the hills of Tuscany descends into an all-out scramble for survival.