Season 3

58 EPISODES • 2021

Season 3 of Desus & Mero was released on January 31 and consists of 58 episodes.

Season 2

Episodes

1: RIGHT OFF THE RIP

Jan 31, 2021

Illustrious guest: Stacey Abrams

2: COOK-'EM-ALL

Feb 4, 2021

Illustrious guest: Freddy Gibbs

3: THAT'S ON Y'ALL

Feb 7, 2021

Illustrious guest: Jazmine Sullivan

4: I SMELL BROKE

Feb 11, 2021

Illustrious guest: Whoopi Goldberg

5: PASSIVE-AGGRESSIVE G.O.A.T.

Feb 14, 2021

Illustrious guests: Zendaya & John David Washington English

6: WE BE HERE, HE BE THERE

Feb 18, 2021

Illustrious guest: Anthony Mackie

7: MOVE TO UTICA

Feb 21, 2021

Illustrious guest: Ludacris

8: BIRD COUSINS

Feb 25, 2021

Illustrious guest: Kelly Rowland

9: THE WILD CRANIUM

Feb 28, 2021

Illustrious guest: Travis "Taco" Bennett

10: EAST COAST REGGIE

Mar 4, 2021

Illustrious guest: Ramy Youssef

11: MAD MOIST

Mar 7, 2021

Illustrious guest: Delroy Lindo

12: DON’T COME TO MY FUNERAL

Mar 11, 2021

Illustrious guest: Eddie Huang

13: PIPES O’CLOCK

Mar 14, 2021

Illustrious guest: Phoebe Bridgers

14: PUFF OF FEATHERS

Mar 18, 2021

Illustrious guest: Eddie Murphy

15: MY LITTLE MULE

Mar 21, 2021

Illustrious guest: 24kGoldn

16: L MACHINE

Mar 25, 2021

Illustrious guest: Kenan Thompson

17: FUTURE HATS

Apr 8, 2021

Illustrious guest: Glenn Close

18: HALF A LIP

Apr 11, 2021

Illustrious guest: Andra Day

19: WEEKEND DAD

Apr 15, 2021

Illustrious guest: Miguel

20: TWERKING FOR NO ONE

Apr 18, 2021

Illustrious guest: J Balvin

21: THE CHEEK DETECTIVE

Apr 22, 2021

Illustrious guest: Issa Rae

22: THE PLATYPUS OF SALADS

Apr 25, 2021

Illustrious guest: Demi Lovato

23: YO FREE KNOWLEDGE

Apr 29, 2021

Illustrious guest: Julian Edelman

24: ONE WOOD

May 2, 2021

Illustrious guest: Taylour Paige

25: WALL OF ZEPPOLES

May 6, 2021

Illustrious guest: Yo-Yo Ma

26: STURDY LIMBS

Jun 20, 2021

Illustrious guest: Lil Nas X

27: WATERMARKED X-RAYS

Jun 24, 2021

Illustrious guest: Yara Shahidi

28: MID-NUP

Jun 27, 2021

Illustrious guest: Don Cheadle

29: FULL BODY TOPPY

Jul 1, 2021

Illustrious guest: Migos

30: MAD HABITAT

Jul 8, 2021

Illustrious guest: Benny Blanco

31: YEARLY BERET BUDGET

Jul 11, 2021

Illustrious guest: Vince Staples

32: KETCHUP & OYSTERS

Jul 15, 2021

Illustrious guest: Barry Jenkins

33: SEA OF UNCLES

Jul 18, 2021

Illustrious guest: Cynthia Erivo

34: BANG YOUR LITTLE HAMMER

Jul 22, 2021

Illustrious guest: H.E.R.

35: STAYING IN THE DRAFTS

Jul 25, 2021

Illustrious guest: Bobby Shmurda

36: SPACE LAW

Jul 29, 2021

Illustrious guest: Matt Damon

37: YIELD TO REBINNERS

Aug 1, 2021

Illustrious guest: Zazie Beetz

38: AKA HARRY NUGS

Aug 5, 2021

Illustrious guest: Eric André

39: THROW THE MID

Aug 8, 2021

Illustrious guest: Idris Elba

40: SCAMMING FEE

Aug 12, 2021

Illustrious guest: Marlon Wayans

41: ORIGINAL HAIRLINE

Aug 15, 2021

Illustrious guest: Chance the Rapper

42: WILD VENOMOUS

Aug 19, 2021

Illustrious guest: John Turturro

43: IT MIGHT BE REGGAETON

Oct 17, 2021

Illustrious guest: Nas

44: NOT GUILTY, YOUR MAJESTY

Oct 21, 2021

Illustrious guest: Lewis Hamilton

45: WILD ROMANTICAL

Oct 24, 2021

Illustrious guest: Baby Keem

46: AFRICAN AMERICAN CHLOROPHYLL

Oct 28, 2021

Illustrious guest: Dave Grohl

47: PRAYER WARRIORS ASSEMBLE

Oct 31, 2021

Illustrious guest: Yvonne Orji

48: TODDLER LEVEL CONFIDENCE

Nov 4, 2021

Illustrious guest: A$AP Rocky

49: CLOWN-LIKE ACTIONS

Nov 7, 2021

Illustrious guest: Cordae

50: WEST INDIAN DAD FEET

Nov 11, 2021

Illustrious guest: Dwayne Johnson

51: OVARY MAJORA

Nov 14, 2021

Illustrious guest: Keke Palmer

52: JUST ASKING QUESTIONS

Nov 18, 2021

Illustrious guest: Jeff Goldblum

53: CO-POTATOING

Nov 21, 2021

Illustrious guest: Kevin Hart

54: A VERY ROASTABLE SHIRT

Dec 2, 2021

Illustrious guest: Tracy Morgan

55: STEAMED STEAK

Dec 5, 2021

Illustrious guest: French Montana

56: SUSHI HOT DOGS

Dec 9, 2021

Illustrious guest: Sandra Bullock

57: 110% POLYESTER

Dec 12, 2021

Illustrious guest: Michael B. Jordan

58: BONG, DONE, FINITO

Dec 16, 2021

Illustrious guests: Keanu Reeves and Carrie-Anne Moss

Season 4

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